BioFragment
Oxford University b2b
BioTech
Oxford, United Kingdom
Contact

Problem: BioFragment addresses the inefficiencies and high costs associated with traditional drug discovery methods. The current process often leads to the wastage of chemical fragments that could otherwise be utilised, which contributes to unsustainable practices and delayed drug development. The pharmaceutical industry is under increasing pressure to adopt sustainable practices while also accelerating drug development. Traditional methods are not only slow and costly but also heavily dependent on toxic materials and heavy metals. There is a critical need for faster, more sustainable approaches that reduce this dependency and improve the efficiency of drug discovery. Specifically, there is a strong demand for sp3-rich drug-like molecules that are synthetically tractable, providing both regio- and stereoselectivity. Moreover, industries such as fragrances and biofuels also seek innovative solutions like the addition of hydroxyl groups to enhance biodegradation. However, scalability remains a significant hurdle, particularly in transitioning from small-scale to industrial-scale production. 

 

Solution: BioFragment provides an innovative enzyme-based technology that converts non-usable chemical fragments into viable drug candidates through the use of biocatalysis, making drug discovery more sustainable, faster and efficient. Our technology, powered by an extensive library of versatile enzymes, addresses the pharmaceutical industry's need for faster, environmentally friendly, and scalable solutions. By leveraging our 10+ years of research, we improve enzyme function prediction, ensuring that our biocatalysts deliver high regio- and stereoselectivity. BioFragment’s approach not only reduces the time and cost associated with traditional drug discovery methods but also meets the growing demand for sp3-rich molecules and more sustainable practices in drug development and beyond. 

 

USP: Our unique selling proposition lies in our proprietary enzyme library, developed over a decade of research, which contains over 3,000 versatile enzymes. Alongside our unique know-how, this allows us to offer highly tailored and efficient solutions for drug discovery that our competitors cannot easily replicate. Furthermore, each new compound contributes to our R&D, enhancing the company's efficiency and potentially providing data to develop a predictive algorithm in the future. 

Next pitch →
October 30-31, 2024
Nominations
In 2024, Stage Two gathers 50+ startups nominated by 40+ university-affiliated entrepreneurship centers and 4 wildcards. All spin-offs will pitch their business models live in front of more than 60+ top European venture capital firms and 30+ industry leaders.
+ € 5 Million
Investments
Skilling & Accelerate
Workshops
Nominees
3D GeoLAB
Warsaw University of Technology
IT
b2b
AdaptX
Technical University of Berlin
Sustainability
b2b
→ adaptx.de/en/
Aisencia
EXIST Wildcard
MedTech
b2b
→ aisencia.de/en/
Algaemical
ESADE
Sustainability
b2b
algaemicalcarbon.com
Anferra
Chalmers University of Technology
Circular Economy
b2b
→ anferra.com/
Belfort
KU Leuven
DeepTech
b2b
→ belfort.eu/
BEMORE3D
UPV Universitat Politecnica de Valencia
Industry 4.0
b2b
→ bemore3d.com/
BioFragment
Oxford University
BioTech
b2b
linkedin.com/company/biofragment/
CupHub
Erasmus University Rotterdam
FemTech
b2c
→ cuphub.net/
DorsiDynamics
Universität Graz
MedTech
b2b & b2c
dorsi-dynamics.com
eGodziny
HR Tech Wildcard
Industry 4.0
b2b
→ egodziny.pl/
Floating Ground
WU Wien
Energy
b2c
floatingground.com
Floodwaive
RWTH Aachen University
Deep Tech
b2b
floodwaive.de
GaltTec
University of Tartu
DeepTech
b2b
→ galttec.com/
GLOOMA
Universidade NOVA de Lisboa
MedTech
b2b & b2c
→ glooma.pt/en
Intraction
Stockholm School of Economics
HR-Tech
b2b
→ intraction.com/
Joulzen
Technical University of Vienna
CleanTech
b2b & b2c
joulzen.at
Micro Factory
TU Munich
Engineering
b2b
micro-factory.de
MOLA
HHL Leipzig - Graduate School of Management
Consumer
b2c
officialmola.com
Myco Farming
VU Amsterdam
CleanTech
b2b
→ mycofarming.nl
Nanomation
University of Cambridge
Engineering
b2b
→ nanomation.tech/
NAYA
NTNU Trondheim
AI
b2b
→ naya.no
Nextract
Siemens Wildcard Winner
CleanTech
b2b
→ nextract-energy.com
OLE Funds
London Business School
FinTech
b2c
olefunds.com
Optiverse
University of St. Gallen
IT
b2b
→ optiverse.ai/
OptoLoc
Heriot-Watt-University
MedTech
b2b
ORis
I3P - Incubator of Politecnico di Torino
Engineering
b2b
→ oris-space.com/
Peekcell
École Polytechnique de Paris
MedTech
b2b
peekcell.fr
PlantSalt
WHU
Agri- & FoodTech
b2b & b2c
plantsalt.de
RayVen
Ruhr University Bochum
DeepTech
b2b
→ rayvenlaser.com/
Riverkin
ETH Zurich
CleanTech
b2b & b2c
riverkin.com
Roadcode
Gdansk University
Engineering
b2b
→ roadcode.net/
Sensera
Universitatea Babeș-Bolyai
MedTech
b2b
Submerge
Riga Technical University
DeepTech
b2b
submergebaltic.com
SunCubes
Politecnico di Milano
DeepTech
b2b
→ suncubes.space/
SUNEY
IE Business School
DeepTech
b2b
Surgerix
University of Eastern Finland
MedTech
b2b
→ sites.uef.fi/humea/humea-laboratory/er4surgery/
Tesoro
Alba Graduate Business School

b2c
Turn-Motion
INiTS Universitäres Gründerservice Wien GmbH
MedTech
b2b
turn-motion.com
UniView
Maastricht University
Real Estate
b2c
→ uni-view.nl/
Upwind
University of Porto
CleanTech
b2b
→ upwind.pt/
Validaitor
KIT Karlsruhe
DeepTech
b2b
→ validaitor.com
W1NNAS
University of Cologne
Sports Nutrition
b2b
→ w1nnas.de/
Wild.Codes
Kyiv School of Economics
IT
b2b
→ wild.codes/
Prizes
100k Media Cash Price
Stage Two Movement Award
The victorious startup will have the opportunity to use a budget of 100k for their media campaign (e.g., Handelsblatt) that they can plan together with DvH Ventures.
1 Mio.
World Fund investment prize
Subject to due diligence by World Fund, one startup individually selected by World Fund gets offered a potential investment worth 1.000.000€.
1 Mio.
IQ Capital investment prize
Subject to due diligence by IQ Capital, one startup individually selected by IQ Capital gets offered a potential investment worth 1.000.000€.
1 Mio.
Seaya investment prize
Subject to due diligence by Seaya, one startup individually selected by Seaya gets offered a potential investment worth 1.000.000€.
850K
HTGF German Deep Tech Award
Subject to due diligence by HTGF, one startup individually selected by HTGF gets offered a potential investment worth 850.000€.
750K
Redstone investment prize
Subject to due diligence by Redstone, one startup individually selected by Redstone gets offered a potential investment worth 750.000€.
500K
b2venture investment prize
Subject to due diligence by b2venture, one startup individually selected by b2venture gets offered a potential investment worth 500.000€.
500K
xdeck investment prize
Subject to due diligence by xdeck, one startup individually selected by xDeck gets offered a potential investment worth 500.000€.
300K
Earlybird investment prize
Subject to due diligence by Earlybird, one startup individually selected by Earlybird gets offered a potential investment worth 300.000€.
250K
AtlanticLabs investment prize
Subject to due diligence by AtlanticLabs, one startup individually selected by Atlantic Labs gets offered a potential investment worth 250.000€.
Skilling
Problem Solving Workshop
The winners of the Stage Two Innovation and Movement awards will receive valuable support, guidance and mentoring from McKinsey & Company.
Skilling
Tech for Good Award
The winners of the Tech for Good award will receive valuable impact management training and coaching from experienced Value for Good impact advisors.
Skilling
Start2explore UAE
The winners of the Start2explore UAE award will receive valuable guidance and coaching from experienced Start2 advisors on their strategic and commercial internationalization.
Accelerate
Fast-track-to-IC
The victorious startup will have the opportunity to learn about what it takes to present directly to the investment committee in a dedicated 1:1 workshop with experienced investors. During this session, it will be determined if SquareOne initiates the due diligence process.
Accelerate
Company building with Chemovator
Chemovator gives you a kickstart into business develpment and company building. Tap into our team's experience, take a shortcut with distilled learnings from our rockstar team and leverage the BASF network!
Accelerate
Fast-track-to-IC
The victorious startup will have the opportunity to present directly to the investment committee. During this session, it will be determined if APEX Ventures initiates the due diligence process.
Accelerate
Fast-track-to-IC
The victorious startup will have the opportunity to present directly to the investment committee. During this session, it will be determined if Armilar VP initiates the due diligence process.
Accelerate
Fast-track-to-IC
The victorious startup will have the opportunity to present directly to the investment committee. During this session, it will be determined if Food Labs initiates the due diligence process.
Accelerate
Workshop
The winners of the Accelerate award will receive valuable guidance and coaching from experienced HV Capital investment professionals on their fundraising and investment strategy.